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Role of human granulocyte stimulating factor in the management of feline panleukopenia infections in domestic cats of Chennai
International Journal of Veterinary Sciences and Animal Husbandry · 2026 · Vol. 11(1S) · pp. 120–124
Abstract
Feline Panleukopenia Virus (FPV) infects felids via fecal-oral route, causing > 90% kitten mortality. In 18 PCR-confirmed cases, cats were grouped (N=6): Group 1 (Filgrastim), Group 2 (conventional: ceftriaxone-tazobactam 20 mg/kg + Vetplasma), Group 3 (combination). Signs included vomiting, diarrhoea, anorexia, leukopenia, neutropenia, thrombocytopenia, elevated creatinine/AST, reduced protein (p<0.001). Combinatory therapy (Group 3) yielded fastest haematology/serum recovery vs. others (p<0.001), controlling secondary infections and dehydration. Filgrastim alone was ineffective. Vaccination is recommended for prevention.
Virus-based gene therapy researchVirology and Viral DiseasesAnimal Virus Infections StudiesCATSVaccinationKittenVirusFilgrastimGranulocyte colony-stimulating factor
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