Exploring the therapeutic landscape of Achyranthes aspera L.: From traditional uses to modern pharmacological applications and phytochemical insights

Abstract

Achyranthes aspera L., often referred to as Apamarg, is a well-respected medicinal plant widely utilized in folk medicine across various cultures. This thorough review consolidates the existing scientific knowledge regarding its diverse phytochemical profile and extensive pharmacological properties. Phytochemical investigations indicate that Achyranthes aspera L. is a notable source of bioactive substances, including alkaloids, saponins, flavonoids, tannins, glycosides, and terpenoids, which collectively support its medicinal capability. This includes demonstrating potent analgesic, anti-inflammatory, anti-diabetic, anticancer, antioxidant, and antimicrobial potential against bacteria, fungi, and viruses. The overall data highlight the fact that Achyranthes aspera L. has significant potential in the context of new drug discovery and therapeutic development. Nevertheless, additional strenuous studies, such as clinical studies, extensive toxicological experimentation, and mechanistic research, should be carried out to maximize its potential as a medicine and to make it easier to implement into the present healthcare system.