A review of herbal therapeutics for the treatment of vitiligo

Abstract

Vitiligo is a depigmenting disease caused by the destruction of healthy melanocytes. Due to side effects and inconsistent outcomes associated with traditional therapies, there is growing interest in herbal therapies for vitiligo. Ixora coccinea and Acalypha indica may be useful treatments for vitiligo. Acalypha indica contains flavonoids, tannins, and alkaloids with anti-inflammatory and antioxidant properties that may protect melanocytes and stimulate melanogenesis. Ixora coccinea contains phenolic compounds, flavonoids, and anthocyanins that may have immunomodulatory and melanin-inducing properties. Based upon their potential to regulate immune response and reduce melanocyte death, both plants may contribute to restoring skin homeostasis. Efficacy and safety studies (clinical and formulation studies) are needed to ensure their effectiveness for treating vitiligo.