Assessment of free radical scavenging activity from ethanolic extracts of arms and suckers of marine cephalopod, Uroteuthis sibogae

Abstract

The present study assessed the free radical scavenging capacity of the ethanolic extracts of arms and suckers of marine cephalopod Uroteuthis sibogae. The free radical scavenging properties of 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging activity, Superoxide anion radical scavenging activity and Nitric oxide radical scavenging activity at five different concentrations was assessed. The inhibition was compared with respective synthetic antioxidants. Free radical scavenging at the highest concentration inhibition yield for DPPH was 51.72 %, Superoxide anion radical scavenging activity 60.92 % and Nitric oxide radical scavenging activity 53.03 % was reported. The results from the present study will be helpful to develop nutraceutical supplements obtained from the bioactive compounds of the arms and suckers the cephalopod species taken for the study. This would provide pharmacophore leads from molluscan species in combating free radical chain formation and being a source of target for degenerative and life style modified disease management.