Tumor of follicular infundibulum in beard area: A case report and literature review

Abstract

Background: Tumor of follicular infundibulum (TFI) is an uncommon, benign adnexal neoplasm without distinctive clinical features. It usually presents as a solitary lesion on the head, neck, or trunk. Histologically, it demonstrates a plate-like epithelial proliferation with thin epidermal connections. Although benign, TFI has clinical importance due to associations with basal cell carcinoma and Cowden’s syndrome. Case Presentation: We report a case of TFI in a 42-year-old male with multiple hypopigmented lesions over the beard area. Histopathology revealed a well-circumscribed lesion with epithelial strands arranged parallel to the epidermis, peripheral palisading of basaloid cells, and focal glycogenation without atypia. Immunohistochemistry was negative for BCL-2 and Ber-EP4, with a Ki-67 index