In vitro antidiabetic activity of Tinospora cordifolia via enzymatic assay

Abstract

The present study evaluates the in vitro antidiabetic potential of Tinospora cordifolia Q using enzymatic inhibition assays. Inhibiting enzymes such as α-amylase and α-glucosidase is considered an effective strategy to delay glucose absorption and manage postprandial hyperglycemia. In this study, varying concentrations of T. cordifolia Q were tested for their inhibitory effects on these enzymes. The results revealed a concentration-dependent inhibition, indicating significant potential of the tincture in moderating carbohydrate breakdown. These findings provide scientific validation to the traditional use of T. cordifolia in managing diabetes and suggest that its mother tincture may serve as a promising natural adjunct for controlling hyperglycemia.