A single case study on ayurvedic management of a child with Duchenne Muscular Dystrophy (DMD)

Abstract

Duchenne Muscular Dystrophy (DMD) is a widely prevalent neuromuscular disorder seen across all ethnic groups, with an occurrence rate of approximately 1 in every 3,500 male births. It is inherited in an X-linked recessive pattern and results from mutations in the gene responsible for producing dystrophin, a protein located on the X chromosome's short arm at the Xp21 locus. The disease typically presents with progressive muscle degeneration, delayed motor milestones, enlargement of calf muscles, and an abnormal increase in connective tissue within muscle fibres.Despite the absence of a definitive cure, several treatment strategies aim to delay the onset and progression of the disorder. This case report discusses the Ayurvedic management of a 14-year-old male having trouble in walking since age 8, along with signs like frequent slipper slipping and gradual muscle weakening. From an Ayurvedic perspective, the condition aligns with Adibalapravritta Vyadhi, caused by Beeja Dushti (genetic abnormalities) and Avayava Dushti (tissue or organ deformities). The continuous deterioration of bodily tissues (Dhatus) triggers Vata Dosha aggravation, which localizes in Mamsa (muscle) and Meda Dhatu (fat tissue), leading to their depletion. Treatment was administered following classical Ayurvedic guidelines, including Snehana (therapeutic oiling), Swedana (sudation), and Matra Basti (oil-based enema), over a period of 15 days. The intervention led to a notable decline in the patient's serum creatine phosphokinase (CPK) levels, reflecting clinical improvement. Although the genetic basis of DMD remains unchangeable, Ayurvedic interventions can contribute to symptom management and better quality of life. The lack of a curative treatment inconventional medicine highlights the importance of exploring and integrating trSSaditional healing systems like Ayurveda.