The human amniotic membrane: From structure to dermatologic innovation

Abstract

The human amniotic membrane (HAM) has emerged as a novel biomaterial in dermatology, offering regenerative, anti-inflammatory, and antimicrobial properties that support its use in both therapeutic and aesthetic applications. This review provides a comprehensive overview of HAM’s anatomical and structural composition, methods of processing, and its unique biological functions. A particular emphasis is placed on its dermatologic applications, including wound healing, psoriasis, skin rejuvenation, pigmentation disorders, Stevens-Johnson Syndrome, and hair regeneration. The article highlights HAM’s potential to innovate clinical practice in dermatology and its growing relevance in tissue-based therapies.