Multiple sclerosis following environmental toxin exposure: A Case report of Camp Lejeune water contamination

Abstract

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system, with an unclear etiology. While genetic susceptibility is recognized, environmental exposures, including to organic solvents, have been increasingly implicated in disease pathogenesis. While MS has multifactorial origins, this case highlights a potential link between early-life environmental toxin exposure and subsequent development of MS. Previous studies have suggested an association between solvent exposure and increased risk of autoimmune diseases. Mechanisms may involve molecular mimicry, oxidative stress, and immune dysregulation. This case adds to emerging evidence supporting environmental contributors to MS pathogenesis. Further investigation into the long-term neurological effects of toxic exposures is warranted to inform public health policies and clinical screening practices.