review Open Access

CT vs. MRI perfusion in stroke imaging: A review of current evidence and emerging technologies

International Journal of Bioscience and Biochemistry · 2025 · Vol. 7(2) · pp. 87–93

Abstract

Acute Ischemic Stroke (AIS) management increasingly relies on advanced imaging to identify salvageable brain tissue (the ischemic penumbra) and guide reperfusion therapy. This review examines and contrasts Computed Tomography Perfusion (CTP) and magnetic resonance perfusion (MRP) imaging in stroke, focusing on diagnostic accuracy, clinical outcomes, and emerging technologies (2018-2025). Key findings from recent studies are summarized: adding CTP to standard CT protocols significantly improves detection of ischemia (sensitivity rising ~19.5%) without compromising specificity, and CTP notably enhanced diagnostic accuracy (residents’ AUC from ~88% to 97%). MRI-based protocols detect strokes with higher sensitivity than CT and substantially reduce treatment of stroke mimics (CTP vs MRI mimic thrombolysis: 8.6% vs 4.3%, p

Advanced X-ray and CT Imaging Advanced MRI Techniques and Applications Radiomics and Machine Learning in Medical ImagingPerfusion scanningStroke (engine)MedicineCurrent (fluid)RadiologyMagnetic resonance imagingPerfusionEngineering

Citations

FWCI

0.00

field-weighted impact

References

Percentile

16%

vs. same field & year

References

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Stroke · 2018 · 5,444 citations

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