Evaluation of antioxidant potential of skin extracts from marine cephalopod, Siboga squid (Photololigo)

Abstract

The present study was characterized for antioxidant potential of the skin ethanolic extracts of Uroteuthis sibogae. The free radical scavenging properties was analysed by (DPPH), ABTS, Reducing power (RP), inhibition of β-carotene bleaching assay and total antioxidant capacity (TAC) at concentrations ranging from 2 to 10 mg/ml. The inhibition was compared with respective synthetic antioxidants. Free radical scavenging at the highest concentration inhibition yield for DPPH was 79.34%, ABTS 90.44 %, RP 91.20%, β-carotene assay was 155.67% and TAC 95.54% was reported. The results from the present study will be helpful to develop nutraceutical supplements obtained from discard of squid which can be used as natural antioxidant to retard the lipid oxidation. This would provide pharmacophore leads from molluscan species in combating free radical chain formation and being a source of target for degenerative and life style modified disease management.