Periodic monitoring of etiological agents of UTI and their resistant pattern against broad spectrum antibiotics in tertiary care Hospital

Abstract

Aim: To identify most common microorganisms causing UTI and the percentages of all highly resistance antibiotics.Objectives 1.To find out the most common resistant groups of antibiotics.2. To find out the most common microorganisms causing UTI.In current scenario what kind of antibiotics are working in UTI patient in tertiary care hospital.Introduction: Urinary tract infection is a very common infection in both gender male and female, it is very common in clinical practices also.It is a known health problem among the community not only in India but across the world, the data shows that in all kind of health care issues UTI is a very common problem, in hospitals, patients who have indwell catheter they may get CAUTI (Catheter associated urinary tract infection) it is also very big issue because where patients are getting their treatment at the time of their hospital stay, they have got another infection of Urinary tract.It has been found that the E.coli and Klebsiella spp.and many other gram negative bacteria are the commonest cause of UTI. Materials and Methods: A Cross-sectional observational study was conducted over a period of One year-in July 2022 to July 2023 in tertiary care hospital among OPD and IPD patients under multispecialty service of the Hospital. Results:The most commonest etiological agent found was Klebsiella spp.rest of it, other microorganisms were Escherichia coli, Enterococcus, candida albicanc, Pseudomonas aeruginosa, Pseudomonas fluorescens and Proteus spp.The number of Urinary tract infected were only 30 out of 100 patients in which we isolated many bacterial spp.They have been infected IPD and OPD patients.The most common pathogens being Klebsiella spp.(56.6%) who have been infected 17 cases, E.coli spp.infected 3 cases (9.6%), Pseudomonas spp.Infected 2 cases (6.45%) Candida spp.infected 2 cases (13.3%),Enterococcus spp.Infected 2 cases (6.45%) and Proteus spp.infected 2 cases (6.6%).Conclusion: This periodic research shows that now a days most of the antibiotics are getting resistant there we can understand through the group of antibiotics like, cephalosporin are getting resistant more than 80% (Cefazolin, Cefixime, Cefotaxime, cefepime and ceftriaxone), Amoxicillin belongs to a group of drugs known as penicillin-like antibiotics and it functions by preventing bacterial growth.Clavulanic acid belongs to a group of drugs known as beta-lactamase inhibitors.It functions by stopping bacteria from breaking down amoxicillin they are also showing 86% of resistance which is (26 times found resistant out of 30 positive cases).