Guillain-barre syndrome presenting with atypical neurological manifestations in L3 vertebral lesion: A case report

Abstract

Guillain-Barre Syndrome (GBS) and other autoimmune illnesses are known to cause symmetrical paralysis and areflexia. An 80-year-old woman with atypical GBS is reported in a case report as experiencing right leg pain, dysarthria, trouble standing, and an L3 cord lesion on MRI. Her neurological conditions appear to have been exacerbated by her medical history, which includes diabetes and hypertension. After an electrical test revealed demyelination and a cerebral fluid evaluation revealed albuminocytologic dissociation, this diagnosis was made. Similar to the aforementioned scenario, GBS necessitates a thorough differential diagnosis in order to distinguish it from structural illnesses like radiculopathy or viral spondylitis. The importance of supportive treatment is shown by the favourable clinical outcomes obtained following complete patient care, which includes physical therapy, pain management, and immunotherapy with IVIg. This example illustrates the clinical variability of GBS and the need for heightened suspicion in atypical presentations. Better patient outcomes in complicated nervous system illnesses depend on early diagnosis and a multidisciplinary approach.