Predictive value of central arterial pressure at the time of primary percutaneous coronary intervention for in-hospital major adverse cardiovascular events after acute ST-segment elevation myocardial infarction

Abstract

Background: STEMI remains a major contributor to morbidity and mortality despite advancements in primary percutaneous coronary intervention (PPCI). Central arterial pressure (CAP), measured during PPCI, has emerged as a potential predictor of MACEs during hospitalization. This investigation aims to evaluate prognostic value of CAP parameters in STEMI patients undergoing PPCI. Methods: This prospective observational study included 115 STEMI patients undergoing PPCI, categorized into non-MACEs (no events) and MACEs (≥1 event). Intraoperative central systolic pressure (CSP), central diastolic pressure (CDP), central pulse pressure (CPP), and central mean pressure (CMP) were recorded, alongside clinical, laboratory, echocardiographic, and angiographic data. Multivariate logistic regression and ROC analysis assessed their predictive value. Results: MACEs occurred in 29.6% of patients. CSP ≥137.5 mmHg (OR = 1.19, P = 0.02) and