Polycystic kidney disease in a persian cat: A case report

Abstract

This case study describes about a 5-year-old male Persian cat presented with history of anorexia, emaciation, and dullness since one week. Clinical examination revealed painless distended abdomen, pale conjunctival mucous membranes, tachycardia and respiratory distress. Hematological analysis indicated anemia and leukocytosis, while serum biochemistry showed elevated blood urea nitrogen (BUN) and creatinine levels. Abdominal ultrasonographic evaluation revealed renomegaly with multiple renal cysts, confirming an advanced-stage polycystic kidney disease (PKD) with irreversible renal failure. Management included Intravenous Ringer’s lactate administration to combat dehydration, Inj. pantoprazole (1 mg/kg) and Inj. ondansetron (0.5 mg/kg) for nausea control, and Inj. darbepoetin alfa (1 μg/kg SC weekly) with Inj. iron sucrose (0.3 mL IV) for anemia. Ipakitine (1 g/5 kg PO BID) was added as a phosphate binder and a renal diet was recommended. Despite supportive therapy, the prognosis was poor, and the cat succumbed to the disease post-discharge. This case underscores the importance of early ultrasonographic screening and genetic testing for PKD in high-risk breeds.