Exploring the therapeutic efficacy of Aloe vera: A pharmacological perspective

Abstract

Plants are a great source of pharmaceuticals because they are the source of many of the treatments that are now on the market. Nevertheless, the healthcare system in poorer nations depends heavily on plants and the products derived from them. Around the world, aloe vera, one of the most well-known medicinal plants, is used to cure or prevent skin conditions, metabolic and cardiovascular diseases, and cancer. Aloe leaf's polysaccharide content has been demonstrated in numerous studies to possess a variety of properties, including as immunomodulation, antibacterial, antiviral, anti-cancer, and anti-inflammatory properties. Because aloe vera is grown all over the world, its precise origin is hard to pinpoint. The Madeira Islands, Algeria, Morocco, Tunisia, and the Canary Islands have all been proposed as sites for the species' naturalised stands. Habitats show that humans dispersed it over the Mediterranean region, which includes parts of southern Australia, eastern and southern Africa, the Mediterranean Sea region of Europe, and the United States. Aloe possesses a wide range of pharmacological properties, including Anti-oxidant activity, Anti-microbial, Anti-aging, Anti-cancer activity, Cardiovascular activity, Ulcer-protective property, Laxative, Skin protection properties. Various compounds have been reported to be purified or identified from Aloe. These identified phytochemicals have reported significant pharmacological effects. This review can widen the understanding regarding phytochemistry, geographical distribution and pharmacological activities of Aloe.