Value of 18F-FDG PET/CT in guiding management of facet joint arthropathy
Abstract
Objectives: This study aims to evaluate the diagnostic utility of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in identifying active disease sites in facet joints in patients with chronic neck and back pain.Methods: A cross-sectional study was conducted on 70 patients presenting with chronic neck and back pain. Patients underwent clinical evaluation, laboratory testing, and imaging assessments, including PET/CT and contrast-enhanced CT. Diagnostic performance metrics such as sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were compared between PET/CT and CT. Results: PET/CT identified active facet joint inflammation in 41.4% of 70 patients, while CT detected degenerative changes in 57.1%. PET/CT demonstrated significantly higher sensitivity (86.7% vs. 42.5%), specificity (92.5% vs. 60.0%), accuracy (90.0% vs. 50.0%), PPV (89.7% vs. 58.6%), and NPV (90.2% vs. 43.9%) compared to CT (p
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