Outcome evaluation of thyroid cancer patients with radical neck dissection operation

Abstract

Introduction: Thyroid cancer is the most common endocrine cancer and its incidence has continued to increase on the last three decades in the worldwide. In thyroid cancer patients with positive lymph nodes, radical neck dissection is generally performed and is associated with worse outcomes. Outcomes can be assessed from overall survival, disease free survival and quality of life in patients. This outcome has varying results in various studies and its important on evaluation the treatment of cancer patients. Objective: To determine outcome evaluation of the thyroid cancer patients that radical neck dissection operation at Dr. M. Djamil Padang hospital. Method: This is an analytical study using retrospective cross-sectional method in the surgical oncology division of Dr. M Djamil Padang hospital in August 2024 - November 2024. This study using medical record data from thyroid cancer patients who underwent radical neck dissection operation at Dr. M. Djamil Padang hospital during the period January 2018 - January 2024. Results: In this study, there were 35 patients who had undergone radical neck dissection operation for more than 5 years with the characteristics 15 men (42.9%) and 20 women (57.1%), aged 55 years were 21 people (60%), papillary type thyroid cancer were 32 people (91.4%), follicular were 2 people (5.7%) and medullary was 1 person (2.9%), clinical stage I were 14 people (40%), stage II were 4 people (11.4%), stage III were 16 people (45.7%) and stage IVa was 1 person (2.9%). There was an overall survival >5 years were 22 people (62.9%), disease-free survival for 5 years were 29 people (82.9%) and quality of life was assessed using the EORTC specific thyroid questionnaire with result complaints of functional were 40.9-77.3% and complaints of psychosocial were 31,8-59,1%. There was a significant association between clinical stage and overall survival with p