Safety evaluation of phytophosholipid complexes of quercetin in Gallus gallus domesticus

Abstract

Quercetin is a plant pigment, that belongs to flavonoid category of phytochemicals. Quercetin has an antioxidant property nonetheless with less water solubility and little bioavailability. In current study quercetin was complexed with phytophospolipid to form phytophospolipid complexes (phytosomes) and current study aims to investigate the its safety, in Gallus gallus domesticus (chicken). The safety study was carried out in healthy broiler birds, as per protocol designed for safety evaluation of compounds and formulations as per OECD guidelines. At the end of study, all the birds were scarified humanely. Necropsy procedure was performed in treatment and control birds to note any gross changes in visceral organs and tissues from these organs were collected for histopathological studies. This study concludes the safety of phytophospolipid complexes in broiler birds.