Prevalence rate of antitussive transglutaminase antibodies in type 1 diabetic children

Abstract

Background: The association of celiac disease and type I diabetes mellitus is known worldwide due to shared auto immunological background, since celiac disease could present in diabetic patients with nonspecific symptoms or asymptomatically, so follow up and screening is necessary for early diagnosis. To estimate the prevalence of celiac disease in children with TIDM. Methods: This is a cross sectional study comprised all the Validate diabetic children seen in our wards, emergency unit consultation department in AL Zahraa Teaching Hospital for Maternity and Child health in AL Najaf AL-Ashraf city from November 2015 through October 2016. Results: We enrolled 53 children with TIDM (25 males and 28 female) age of patients in this study ranging from I.3/12 to 15 years. Anti-tissue transglutaminase antibody was positive in 7/53 patients, more in girls (5/28), (2/25) of boys, making the prevalence of celiac disease 13.2%. Female number more than male, but without statistical significance. Anti-tissue transglutaminase antibody was positive in 7/53patients, more in girls (5/28), (2/25) of boys, making the prevalence of celiac disease 13.2%. Female number more than male, but without statistical significance. Conclusion: The prevalence of celiac Disease in type I diabetes mellitus in our study show a relatively high prevalence compared with other studies. Therefore, screening and follow up of patients by Anti tissue transglutaminase antibodies is recommended for all patients with type I diabetes.