Spectrophotometric method for determining Paracetamol in aqueous and pharmaceutical formulations using oxidation by potassium ferricyanide and coupling with sodium tungstate

Abstract

To quantify paracetamol and its several medicinal formulations in an aqueous solution, a spectrophotometric approach was suggested. Paracetamol is oxidized by potassium ferricyanide and then coupled with sodium tungstate in a basic media as the basis for the procedure. The aqueous solution with a brown dye has the maximum absorption at 565 nm. It was discovered that the molar absorptivity was (2569.89 L/mol. cm) and that it complied with the law of beer between 1 - 65 µg/mL. The assay of pills, syrup, and ampules is accomplished with success using this technique.