Serum vitamin D in rheumatoid arthritis patients: Its relation to disease activity and neuropathic pain

Abstract

Vitamin D is involved in regulating the immune system through various processes, thereby indicating that a vitamin D deficiency contributes to the development and progression of rheumatoid arthritis. People with a vitamin D deficiency frequently experience heightened pain sensitivity, a condition linked to hyperinnervation and hypersensitivity in nerve fibres. The trial's primary goals were to measure the levels of vitamin D in rheumatoid arthritis patients' blood and look for any connections between the vitamin and the severity of the condition. Using nerve conduction study (NCS) as a marker, the trial also aimed to determine a relationship between vitamin D levels and neuropathic pain in RA patients.