Case report: Efficacy of combine therapy of betahistine dihydrochloride & pentoxifyllin in the treatment of peripheral vestibular syndrome in dog

Abstract

Geriatric canine vestibular illness/idiopathic vestibular syndrome, sometimes referred to as old dog vestibular sickness, is the most common cause of acute unilateral peripheral vestibular dysfunction in older dogs. The disease is characterized by ataxia with a horizontal or rotatory nystagmus, head tilt, and loss of balance. The majority of experts characterized IVS as a peripheral vestibular illness that can affect cats of any age and elderly canines and is acute to peracute, improving, and non-painful. Assessing the effectiveness of pentoxifylline and betahistine HCL combination therapy in the treatment of canine idiopathic/geriatric vestibular illness was the aim of the study and case report. A 12-year-old dog, sex-male, breed-Mongrel, weighing 18 kg was presented to, PetVet clinic, kalyan-421301 with complaint of imbalance while waking, one side head-tilt, occasional vomiting and pruritic in left ear in the last 6 days. With the help of diagnostic aids available as well as differentiating presented clinical signs as against other differentials, the presented case was diagnosed as, geriatric canine vestibular illness/idiopathic vestibular syndrome. Along with fluid therapy and anti-emetics, this study used novel approach with usage of combination therapy of pentoxifylline and Betahistine Hcl for the treatment. Within 5 days of initiation of therapy dog started to balance its body with normal gait. There was absence of head tilting towards any ear and vomiting was also reduced considerably and other associated symptoms were also decimated with complete recovery in affected dog in 12 days. No reoccurrence of signs were observed.