Long-term outcomes of microneedling and CGF on hair regrowth in patients with androgenetic alopecia a clinical evaluation

Abstract

Background: A common disorder causes its victim to suppress their self-esteem and to affect their physical health. Androgenetic alopecia refers to pattern hair loss in men and women. It is a disorder of hormonal imbalance that is related to genes. Concentrated growth factor (CGF) combined with a modern medical tool; microneedling are very effective therapeutic approach to treat this unwanted disease. Objective: This study primarily aims to determine the long-term outcomes of microneedling and CGF on hair regrowth in patients with diagnosed androgenetic alopecia serving some secondary objectives like gender and age-related impacts on androgenetic alopecia. Methodology: Two-year evaluation on androgenetic alopecia on a sum of 20 healthy patients. The clinical management team collected the patient's plasma samples to prepare CGF factors and to inject it carefully into the study subject’s scalp by 1.5-2 mm microneedles. Data was collected manually on CRF and analyzed by MS Excel and SPSS version 20.0. Graphical representation with p-value determination has been done to represent the study data. Results: This male-dominant study ended with a 1:5.67 ratio of females and males where the p=0.0001 value indicates that intervention therapy is highly significant for patients with androgenetic alopecia. The significance of the age factor, p>0.05 shows that there is no relationship between microneedling and CGF on hair regrowth and patient’s long-term effectiveness. No remarkable adverse reaction is noted in this study. Conclusion: The present study concluded with a promising hair regrowth technique for patients with androgenetic alopecia. It contributes to a better long-term clinical outcome regarding the therapy and patient satisfaction.