Evaluation of the efficacy and outcome of extended endoscopic endonasal approach for resection of skull base tumors

Abstract

Background: Endoscopic endonasal surgery represents a minimally invasive approach that enables surgeons to access and treat various lesions located at the skull base through the nasal cavity. The objective of this study was to assess the outcomes associated with the extended endoscopic endonasal technique in patients diagnosed with skull base tumors, focusing on its safety and effectiveness. Methods: This investigation involved 20 patients presenting with midline skull base lesions, including craniopharyngiomas with intrasellar and moderate suprasellar components, large or giant pituitary adenomas extending significantly into the suprasellar region and anterior cranial base, recurrent skull base masses, and small lesions measuring less than 3-4 cm without lateral extension beyond the optic nerves. Results: Notable improvements were observed in the visual field function of the patients. Statistically significant differences were identified between the preoperative and postoperative functional outcomes (p0.005). Conclusions: The extended endoscopic endonasal approach represents a minimally invasive, safe, and less traumatic surgical technique for managing patients with various skull base tumors.