Post operative oxygen saturation in patients with intraperitoneal instillation of injection ropivacaine 0.375% versus placebo on postoperative analgesia for laparoscopic abdominal surgery: A comparative study

Abstract

The main advantage of using local anaesthetics is that they do not have the adverse effects of opioids, which may delay recovery and discharge from hospital. These effects include postoperative nausea, vomiting, sedation, impairment of return of gastrointestinal motility and pruritus. Many local anaesthetics in various concentrations are used in practice including lignocaine, bupivacaine the latest being ropivacaine. Ropivacaine has shown to be less toxic to cardiac and central nervous system as compared to other drugs. Study was conducted on 60 adult Patients scheduled for elective laparoscopic abdominal surgery at Basaveshwara Medical College and Hospital, Chitradurga for 18 months. Trocar site infiltration and intraperitoneal instillation in the gallbladder fossa and subdiaphragmatic hepatic surface using ropivacaine (35 ml of 0.375%) and bupivacaine (35 ml of 0.25%) at the end of surgery as a part of multimodal analgesia provide safe and effective somato-visceral analgesia in patients undergoing LC. Ropivacaine provides a more profound and prolonged analgesia as compared to bupivacaine.