Accuracy of thyroid ultrasound in the diagnosis of papillar thyroid carcinoma based on paraffin blocks at Dr. M Djamil Hospital Padang

Abstract

Introduction: Papillary thyroid carcinoma (PTC) constitutes 90% of all thyroid malignancies. Ultrasound (USG) is the first modality which inexpensive, non-invasive and widely available to detect thyroid malignancy. The thyroid ultrasound scoring system using the ACR-TIRADS criteria is very effective and has proven to be the best among other scoring systems in differentiating benign from malignant nodules. However, study results regarding this system are still few and varied in papillary thyroid carcinoma.Objective: To determine the diagnostic accuracy of thyroid ultrasound in the diagnosis of papillary thyroid carcinoma based on paraffin blocks at Dr. M. Djamil Hospital PadangMethod: This is a cross-sectional study conducted at Dr. M. Djamil Hospital in January 2023 – June 2024. This study used medical record data from patients with suspected to have PTC who had undergone ultrasound and paraffin block examinations at Dr. M. Djamil Hospital Padang since 01 January 2023 until 30 June 2024. Results: In this study, 26 respondents were found with suspicion of papillary thyroid carcinoma. On histopathological examination, 22/26 samples were diagnosed with papillary thyroid carcinoma, and 4/26 samples had histopathological results other than PTC. In the PTC group, 2/22 respondents were TIRADS 2; 6/22 respondents TIRADS 3; 7/22 respondents TIRADS 4; and 7/22 respondents TIRADS 5. In the non-PTC group, 2/4 respondents had TIRADS 2 and 2/4 respondents TIRADS 3. The accuracy, sensitivity and specificity of ultrasound examination of the histopathology of papillary thyroid carcinoma were respectively 84, 6%; 91% and 50%.Conclusion: Ultrasound examination using the ACR-TIRADS criteria scoring system has quite high accuracy in diagnosing papillary thyroid carcinoma.