Mostua hirsuta (Geselmiaceae) extract stimulates the reproductive and cardiovascular systems in male Wistar rats

Abstract

A species' ability to reproduce itself by transferring life and creating new living beings is a fundamental process that ensures its survival. Unfortunately, many couples experience infertility, among other reproductive health difficulties. The primary goal of this study was to see how extracts from Mostuea hirsuta affected the reproductive system of wistar rats.The various aqueous extract doses were determined based on traditional healers' guidance. The mice received different doses of Mustuea hirsuta aqueous extract (6, 12, and 18 mg/kg) every day for 30 days. The rats received the medicine for thirty days and were weighed every two days. At the end of the thirty days, the rats were slain, and their organs and blood were collected for analysis in accordance with normal protocols.The study found that providing Mostuea hirsuta extract at a dose of 12 mg/dL significantly enhances blood testosterone levels and sperm density in seminal fluid. Asparatate aminotransferase and alanine aminotransferase, two indicators for liver and kidney function, as well as blood cell counts, showed no detrimental effects from varied doses of the extract. Furthermore, the varied extract doses increased both total and HDL cholesterol levels. A phytochemical test found that Mostuea hirsuta extract has naturally high levels of tannins, flavonoids, and polyphenols.The current study's findings back up the traditional use of Mostuea hirsuta extract in the treatment of male infertility.