Synthesis and characterization of hydrazone derivative and its antibacterial, antifungal, antimalarial and antituberculosis activity studies

Abstract

In this study, 2-hydroxyacetophenone-4-hydroxy benzohydrazone (HAHBH) was synthesized by the condensation reaction of 2-hydroxy acetophenone and 4-hydroxy benzohydrazide in the presence of glacial acetic acid. This hydrazone compound was characterized through IR, 1H-NMR and 13C-NMR and Mass spectroscopic measurements and Elemental analysis. The synthesized compound has shown Antibacterial, Antifungal, Antimalarial and Antituberculosis Activity.