Assessment of the anti-inflammatory activity of Methanolic extract of green algae Codium bursa
Abstract
The present study is aimed to evaluate in vivo the anti-inflammatory of methanolic extract of green algae Codium bursa (MEC) on carrageenan induced paw edema model in rats. The experimental protocol was performed on 20 rats divided in 4 groups: a control group, carrageenan-treated group (1%), the reference drug diclofenac sodium (DICLO 100 mg/kg) and MEC-treated group (50 mg/kg). The evaluation of the anti-inflammatory effect of MEC and DICLO was mainly evaluated by the measuring of edema paw swelling, hematological parameters, micronucleus test, oxidative stress assays, and histological evaluation. The pretreatment with MEC showed a significant (p
Funding
- Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche
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