Minoxidil in the treatment of alopecia areata

Abstract

Alopecia areata (AA) refers to a chronic inflammatory condition that causes non-scarring hair loss. It could impact hair on the scalp, beard, as well as eyebrows/eyelashes, or it can manifest as a more widespread condition. Using minoxidil in treating AA is biologically justified due to its capacity to reduce DNA synthesis along with leukocyte inhibitory factor within lymphocytes, without impacting their viability or migratory behavior. As a result, they inferred that minoxidil could exhibit a localized immunosuppressive impact that stimulates hair regrowth among individuals developing AA when administered topically. Utilizing a combination treatment with substances like minoxidil may result in a synergistic impact on promoting hair growth.