Evaluation of dry eye syndrome after advanced technique of radiation therapy in head and neck cancers

Abstract

Aim: To assess structural and functional abnormalities of the ocular surface post radiation in head and neck cancers. Objective: To assess the presence and severity of dry eye symptoms according to Ocular Surface Disorder Index (OSDI) questionnaire and Dry eye severity grading by DEWS 2007 classification in patients who underwent radiotherapy for head and neck cancers. To evaluate correlation between dose of radiation therapy and severity of Dry Eye Syndrome by various clinical methods of evaluation of dry eye. Design: Observational case control study. Methods: Participants considering 10% non-response a sample size of 85+8.5=100 subjects with head and neck cancer undergoing radiation. Data analysed using SPSS 22 version software. Chisquare used as test of significance. Independent t test will be used as test of significance to identify the mean difference. p value