A retrospective study on Henoch-Schönlein purpura

Abstract

Henoch-Schönlein Purpura (HSP) is a systemic vasculitis primarily affecting children, characterized by palpable purpura, arthritis, abdominal pain, and renal involvement. Henoch-Schönlein purpura is a prevalent form of vasculitis that mostly affects children, but may also occur in adults. The medical symptoms are believed to result from the deposition of IgA in the blood vessel walls of the afflicted organs, namely the skin, gastrointestinal system, joints, and kidneys. Corticosteroids may be useful in quickly resolving renal symptoms and alleviating joint and gastrointestinal pain. However, there is little evidence to support their effectiveness in treating organ manifestations and consequences, such as glomerulonephritis, bowel infarction, or intussusception. This study aims to provide a comprehensive overview of HSP, including its epidemiology, pathophysiology, clinical manifestations, diagnostic criteria, and management strategies. By synthesizing current research and clinical findings, this paper seeks to enhance understanding and improve patient outcomes.