Solvent-based comparative analysis of antioxidant and antimicrobial activities in Calliandra haematocephala extracts

Abstract

Calliandra haematocephala flowers were evaluated for their phytochemical composition, antioxidant activity, and antimicrobial properties to explore their potential health benefits. The study employed both cold and hot extraction methods with various solvents to assess the presence of bioactive compounds. Phytochemical screening revealed the presence of flavonoids, tannins, and phenols. The antioxidant activity, evaluated through DPPH, FRAP, and ABTS assays, indicated that cold extracts generally exhibited superior antioxidant activity compared to hot extracts, with the highest activity observed in cold ethyl acetate and acetone extracts. Antimicrobial testing demonstrated notable activity of ethyl acetate extracts against Bacillus subtilis, Staphylococcus aureus, and Escherichia coli. The results suggest that Calliandra haematocephala flowers possess significant antioxidant and antimicrobial properties, with cold extraction methods providing the most potent extracts. These findings underscore their potential for use in therapeutic applications and further research.