Organoids: Revolutionising research and shaping the future of medicine

Abstract

The aim of this study is to determine the chemo profile of the aqueous extract of Nauclea latifolia using GC-MS. The GC-MS analysis of the plant extract was performed using a GC-MS QP-2010 (Shimadzu), and the mass spectra of the compounds found in the extract were matched with the data in the National Institute of Standards and Technology (NIST) library. The results revealed the presence of eighteen compounds. The most prevailing compounds were 9-Octadecenoic acid (Z)-methyl ester, Oleic acid, and Benzamide, 2-bromo-N-[2-(3-fluorophenyl)-5-benzoxazolyl], with percentage areas of 16.93%, 14.01%, and 9.18%, respectively. The least abundant compound was 5-methyl-2-phenylindolizine (0.66%). Some of these phytocompounds exhibit bioactivities such as anti-inflammatory, antibacterial, and antimalarial activities. Consequently, the leaf extract has the potential to be a source of novel treatments. The results of this investigation thus validate the plant's traditional usage for medicinal purposes.