A study to determine the association between elevated maternal serum β-hCG levels and HDP

Abstract

Aim: The objective of the present study was to determine the association between elevated maternal serum β-hCG levels and HDP, the correlation between serum β-hCG level and severity of preeclampsia and to determine the value of serum β-hCG level as a diagnostic marker for early diagnosis of HDP. Methods: A hospital's Obstetrics and Gynecology Department did this research. A 12-month observational study. Ethics committee permission was obtained. This research included 150 pregnant women: 100 with hypertension problems and 50 as controls. Both groups had their serum β-hCG levels tested and compared. Results: Twenty (20%) of 100 hypertensive women had prenatal hypertension, 22 (22%) had non-severe preeclampsia, 40 (40%) had severe, and 18 (18%) had antepartum. Control group normotensive moms averaged 25.85 years, whereas research group hypertensive mothers averaged 24.48 years. Mothers with HDP exhibited a significantly higher mean SBP (150.70±18.72 mmHg) compared to normotensive mothers (110.40±10.15 mmHg) (p< Significantly, hypertensive women had a mean DBP of 105.66±12.48 mmHg, whereas normal mothers had 75.5±5.50 mmHg (p<0.001). Significant difference (p<0.001) in proteinuria levels was observed between the two groups. Conclusion: Early detection and treatment may reduce maternal and fetal mortality and morbidity from HDP. Compared to normotensive women, pregnancy-related hypertension was linked to higher blood β-hCG levels. In severe preeclampsia and primigravid hypertensive mothers, the levels are higher than in multigravida.