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Therapeutic potential of N-acetylcysteine in mitigating colitis induced by nonsteroidal anti-inflammatory drugs in Rat models
International Journal of Biology Sciences · 2023 · Vol. 5(2) · pp. 80–83
Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic and anti-inflammatory properties but are associated with gastrointestinal side effects, including colitis. N-acetylcysteine (NAC), a known antioxidant and mucolytic agent, has been investigated for its potential protective effects against NSAID-induced colitis. This article explores the therapeutic potential of NAC in mitigating colitis induced by NSAIDs in rat models, highlighting its mechanisms of action, experimental findings, and clinical implications.
Liver Disease Diagnosis and TreatmentClinical Nutrition and GastroenterologyNonsteroidalAcetylcysteineColitisPharmacologyMedicineAnti-inflammatoryInternal medicineChemistryBiochemistryAntioxidant
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