Anesthesia challenges in pregnancy with neurofibromatosis type 1: A case report

Abstract

Neurofibromatosis is a multisystem disorder with a relentless course. It poses a particular challenge to the anesthesiologist due to involvement of airway, spine, central and peripheral nervous system with systemic neurohormonal implications that can all lead to an adverse intraoperative course. Hence an understanding and detailed evaluation of systemic and local involvement of NF-1 is essential. Pregnancy has additional implications in a patient of NF-1, with an increase in size of neurofibromas, IUGR, preterm labour, hypertension secondary to pheochromocytoma, to name a few. We present the case of a 38 weeks pregnant 29-year-old female with NF-1 who underwent LSCS under spinal anesthesia and had an uneventful recovery. Our aim is to understand the anesthesia implications of NF- 1 and present our unusual case.