Prevalence and clinical characteristics of Egyptian patients with myocardial infarction with non-obstructive coronary arteries

Abstract

Objective: Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) is the presence of the universal acute myocardial infarction (AMI) criteria, stenosis less than 50%, and no overt cause for the clinical presentation at the time of angiography. Diagnosis of MINOCA may require multiple diagnostic tools, including cardiac imaging or provocative tests, in addition to standard coronary angiography, according to clinical suspicion. The aim of this study is to assess the prevalence and predictors of myocardial infarction with non-obstructive coronary arteries in Egyptian patients. Methods: This prospective and observational study was conducted in Tanta university hospital and El Zeitoun specialized hospital from April 2022 till April 2023. All patients who were ≥18 years old, diagnosed with MI according to the Fourth Universal Definition of Myocardial Infarction, and undergone Coronary Angiography included in the study while patients with history of revascularization (PCI or CABG) or diagnosed as MI type 4 or 5 excluded from our study. Results: 844 patients diagnosed with MI and had undergone CA were screened between April 2022 and april 2023. The prevalence of MINOCA was 8.06% (n=68) in our study. MINOCA patients were found to be younger, had a higher incidence of the female gender. MINOCA patients has lower incidence of risk factors such DM, HTN, smoking and dyslipidaemia (p