Expert perspectives on the prescription practice of artificial tears for the management of dry eye disease in Indian settings

Abstract

Objective: The present survey-based study aims to gather expert opinion regarding the clinical use of artificial tears in managing dry eye disease (DED) in Indian settings, with a special focus on sodium hyaluronate.Methodology: The study utilized a multiple-response questionnaire-based survey comprising 24 questions designed to collect feedback, clinical observations, and experiences from specialists regarding the treatment of DED using artificial tear compositions in routine settings. The questionnaire was structured to capture insights on the frequency of use, perceived efficacy, adverse effects, and preferences for specific tear compositions. Data analysis was conducted using descriptive statistics.Results: The survey involved 194 participants. Approximately 39% indicated a preference for diagnosing DED using a slit lamp examination, while 38% favored the Schirmer score method. Around 36% of the experts identified sodium hyaluronate eye drops as the primary choice for treating moderate DED, with a substantial 72% recommending sodium hyaluronate for managing severe cases. Additionally, 37% of clinicians suggested switching to sodium hyaluronate for patients unresponsive to carboxymethylcellulose (0.5%) eye drops. Trehalose emerged as another preferred option for severe DED, endorsed by 51% of clinicians.Conclusion: This study highlighted the preference for artificial tears, particularly sodium hyaluronate, in the treatment of moderate to severe DED. Sodium hyaluronate was identified as the first-line therapy for DED and was considered safe for patients who do not respond well to carboxymethylcellulose. Trehalose has been recommended as another preferred option for severe DED.