Review on pharmacological activity (inflammation) of plant extracts & green synthesized Ag nanoparticles

Abstract

The aim of this review research was to evaluate the anti-inflammatory activity of the extract of Tinospora cordifolia (Guduchi), Aloe vera, Withania somnifera and its green nanoparticles derivatives (Ag, Au etc). Tinospora, Cordifolia (Guduchi) is a large, glabrous, perennial, deciduous, climbing shrub of weak and fleshy stem found throughout India. It is a widely used plant in ancient era and Ayurvedic systems of medicine. The chemical constituents reported from this shrub belong to different classes, such as alkaloids, diterpenoid lactones, glycosides, steroids, sesquiterpenoid, phenolics, aliphatic compounds and polysaccharides. Withania somnifera is commonly known as Ashwagandha. It belongs to Solanaceae family. It has anti-arthritic, anti-bacterial, anti-dote for scorpion sting, anti-stress, anti-tumour and anti-cancer activities. Potential medicinal properties of T. Cordifolia (Guduchi) and Withania somnifera extract reported by scientific research include anti-diabetic, antipyretic, antispasmodic, anti-inflammatory, and even in anti-arthritic, antioxidant, anti-allergic, anti-stress, antimalarial, hepato-protective. Biosynthesis of silver nanoparticles (AgNPs) from silver nitrate solution using water extract of Myrmecodia pendans (Sarang Semut) at room temperature was successfully carried out. The AgNPs obtained were characterized by UV-vis, XRD, FT-IR, SEM and TEM. The typical surface Plasmon resonance of the Ag NPs was observed at around 448 nm.