Green chemistry approaches in pharmaceutical manufacturing

Abstract

Green chemistry is an innovative approach aimed at designing chemical products and processes that reduce or eliminate the use and generation of hazardous substances. In pharmaceutical manufacturing, green chemistry offers significant potential for reducing environmental impact, improving process efficiency, and enhancing sustainability. This paper explores various green chemistry strategies in the pharmaceutical industry, including solvent use, atom economy, catalysis, and continuous processing. Case studies of sitagliptin and ibuprofen synthesis demonstrate the practical benefits of green chemistry. Despite adoption barriers, ongoing advancements and a commitment to education and innovation are critical for realizing a sustainable future in pharmaceutical manufacturing.