Drug prescription in kidney disease: Essential knowledge

Abstract

Kidney disease is a significant global health burden. Drug-induced renal toxicity contributes to acute kidney injury and chronic kidney disease worldwide. Conversely, altered kidney function affects the pharmacokinetics of drugs. Hence, causing drug toxicity. In this review, we discuss prescription of common nephrotoxic drugs in patients with underlying renal impairment, focusing on the pathophysiology of toxicity and preventive strategies available to avoid toxicity.