Sedative and analgesic effect of Butorphanol-xylazine-ketamine anesthesia in rabbits

Abstract

This study was conducted to evaluate the effects of intramuscular (IM) administration of Butorphanol-Xylazine-Ketamine combination for diagnostic and surgical procedures in rabbits. Five rabbits were included in present study undergoing surgical procedures. Basic physiological parameters, analgesic and sedative scores were recorded at 0, 10, 20, 30, 40, 60. Single intramuscular injection of butorphanol (0.1 mg/kg)-xylazine (5 mg/kg)-ketamine (15 mg/kg) was given. The parameters like rectal temperature (RT), depth and rate of respiration (RR), heart rate (HR), oxygen saturation (Spo2) and reflexes were recorded. Butorphanol found to improve sedation and postoperative analgesia of xylazine-ketamine combination in rabbits.