Assessment of ibuprofen toxicity on haematology of fish Cyprinus carpio

Abstract

Water, crucial for human survival, faces constant degradation due to the release of various pollutants like pharmaceuticals, heavy metals, pesticides, and human activities. Present study observed behavioural and haematological changes in freshwater fish, Cyprinus carpio, after exposure to a sublethal concentration of Ibuprofen. To assess the impact of ibuprofen, the LC50 was calculated at different time intervals ie 24 hrs, 48 hrs, 72 hrs, and 96 hr. Lethal concentration was observed 0.23 ml/L. Further investigation involved administering a sublethal concentration of ibuprofen 1/10th of LC50, i.e., 0.023 ml/L to the fish. After exposure to over 7, 14, 21, and 28 days in treated four sets, significant behavioural alterations in C. carpio were observed. Haematological parameters as RBC count, haemoglobin levels, and haematocrit percentage, decreased significantly (p