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Squamous cell carcinoma in hf crossbred cattle: Clinical features and haematological considerations

Abstract

Squamous cell carcinoma (SCC) poses a significant threat to Holstein-Friesian (HF) crossbred cattle, impacting both their well-being and agricultural productivity. This study aimed to comprehensively characterize the clinical features of SCC in HF crossbred cattle and evaluate hematological parameters to assess disease progression. A total of 12 HF crossbred cattle diagnosed with SCC were included in the study, with clinical examinations revealing a predominance of ocular and vulvar tumors exhibiting varied gross appearances, ranging from tennis ball-like to cauliflower-like growths. The presence of ulceration and maggot infestation in long-standing cases underscored the chronic nature of the disease. Hematological analyses indicated that parameters remained within normal ranges, despite intralesional cisplatin administration, suggesting limited hematological influence from treatment. These findings highlight the diverse clinical presentations of SCC in HF crossbred cattle and emphasize the importance of implementing comprehensive diagnostic approaches for effective disease management and control in agricultural settings.

Microbial infections and disease researchCrossbreedBasal cellCarcinomaOncologyInternal medicineMedicinePathologyCancer researchBiologyAnimal science
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