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Chemical composition, traditional uses and pharmacological potential of Podophyllum hexandrum: An endangered medicinal plant of North-Western Himalayas

Zahid AltafTahir MushtaqPA SofiPeerzada Ishtiyak AhmadAR MalikAmerjeet SinghM. Iqbal JeelaniSabira NissarJauhar RafeeqPeerzada Tabish Fayaz

Abstract

Podophyllum hexandrum Royle is a useful medicinal plant and is found in the lower Himalayan zone at elevations between 2000 and 4500 meters. This herbaceous perennial plant has a number of secondary metabolites that are significant from a pharmacological standpoint. The most significant of them is podophyllotoxin, which is utilized to treat specific types of cancer and has cytotoxic and antitumor effects. Due to its vast medicinal potential, plants are also valued in many traditional medical systems. The frequency of this species has decreased in recent years due to overexploitation of the plant. The botanical, medicinal, phytochemical and pharmacological features of the plant are briefly reviewed in this article.

Plant-derived Lignans Synthesis and BioactivityPhytochemistry and Bioactivity StudiesPhytochemistry and Biological ActivitiesPodophyllumEndangered speciesTraditional medicineComposition (language)Medicinal plantsBiologyBotanyChemistryHabitatEcology
Citations
1
FWCI
0.23
field-weighted impact
References
26
Percentile
54%
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Chemical composition, traditional uses and pharmacological potential of Podophyllum hexandrum: An endangered medicinal plant of North-Western Himalayas · Scinovex