A histopathological study to evaluate the role of immunohistochemical technique for evaluating follicular thyroid cancer among cancer patients in Dhi Qar Governorate

Abstract

Background: Despite rising rates of well-differentiated thyroid cancer, follicular thyroid carcinoma is becoming less common. This paper examines the evolution of morphological and immunohistochemical diagnostic criteria to explain why this phenomenon occurred. Follicular thyroid tumors. This article will cover the differences between follicular carcinoma, follicular adenoma, follicular variant of papillary carcinoma, and poorly differentiated carcinoma. It will also discuss the newly defined categories of follicular tumors: follicular tumor of uncertain malignant potential, well-differentiated tumor of uncertain malignant potential, and well-differentiated carcinoma, not otherwise specified. Finally, interesting molecular biomarkers will be examined in relation to histopathological categorization for their prognostic and therapeutic implications.