A retrospective study on the analysis of intestinal tumors using histology and p53 expression

Abstract

Background: The World Cancer Report ranks colorectal cancer as the second most common malignancy globally. The incidence of intestinal neoplasms varies globally, and it seems that environmental variables, rather than heredity, are the primary determinant of this condition. Colorectal cancer is far less common in our country than in the West.Materials and Methods: Out of 1,189 cases reported at the Department of Pathology, Madha Medical College and Research Institute in Chennai, Tamil Nadu, India, 91 cases of intestinal neoplasms were included in this study. The patients were diagnosed between February 2017 and January 2018. Of the 91 specimens, 30 were endoscopic biopsies and 61 were acceptable. Age, sex, symptoms, colonoscopy results, and lesion site were carefully considered in the analysis of detailed patient histories. Results: Tumors of the intestinal tract are among the most common types of neoplasms that can be found. These tumors display a vast variety of histological patterns, a variety of clinical presentations, a large variety of physical patterns, and a tremendous range of prognosis. The small intestine is responsible for 0.3% of all malignancies, while the large intestine is responsible for 2.91 percent. Conclusion: The pathology department conducted this study in retrospect. Reputable intestinal tumor tissues and samples were used in the inquiry.