Association between C-reactive protein to serum albumin ratio and thrombus load in patients with acute myocardial infarction

Abstract

Background: The C-reactive protein (CRP) to albumin ratio (CAR) is considered to provide a more precise measure of inflammatory state compared to CRP or albumin separately. Additionally, CAR has been linked to a less favorable outcome for individuals with critical conditions and malignancies. The purpose of the research was to correlate the CRP to CAR with the extent of coronary artery disease (CAD) in non-ST segment elevation myocardial infarction (NSTSEMI) patients. Methods: The current work was carried out on 100 individuals aged from 40 to 68 years old, both sexes, with clinical criteria of NSTSEMI. Resting 12 electrocardiogram (ECG) leads, transthoracic echocardiography (echo), diagnostic coronary angiography and SYNTAX score (SS) calculation were assessed in all patients. Results: The cut off value of >24.39 × 100 CAR yielded a sensitivity of 40.82%, a specificity of 96.08%, a positive predictive value (PPV) of 67.5% and a negative predictive value (NPV) of 63.3% in prediction of intermediate-high SS (>22) with AUC of 0.708 and P =